Toxicological profiles - 2-butoxyethanol and 2-butoxyethanol acetate

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Exposure profiles were also composed of multiple metrics, including potential emission rate, overall persistence, and long-range transport potential. Hazard and exposure profiles were compared to decision criteria in order to classify the hazard and exposure potentials for each organic substance as low, moderate or high.

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Additional rules were applied e. A risk matrix was used to assign a low, moderate or high classification of potential risk for each substance based on its hazard and exposure classifications.


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ERC classifications of potential risk were verified using a two-step approach. The first step adjusted the risk classification outcomes from moderate or high to low for substances that had a low estimated rate of emission to water after wastewater treatment, representing a low potential for exposure. The second step reviewed low risk potential classification outcomes using relatively conservative, local-scale i. ERC uses a weighted approach to minimize the potential for both over- and under-classification of hazard and exposure and subsequent risk. The balanced approaches for dealing with uncertainties are described in greater detail in ECCC a.

The following describes two of the more substantial areas of uncertainty. Error with empirical or modeled acute toxicity values could result in changes in classification of hazard, particularly metrics relying on tissue residue values i. However, the impact of this error is mitigated by the fact that overestimation of median lethality will result in a conservative protective tissue residue used for critical body residue analysis.